BioHalo: Forever Chemicals Disrupted by Biology

Startup
Industrial Biotech
Biomaterials
BioHalo engineers microbes for precision biohalogenation, building next-gen fluoropolymers that match PFAS performance while staying biodegradable. Their enzymatic toolkit rewires metabolic pathways to insert single fluorine atoms with atom-level control, creating safe, high-value materials.
Dr. Nicolas Krink
Founder & CEO of BioHalo
Prof. Pablo Ivan Nikel
Co-Founder & Group Leader at Technical Uni. of Denmark
Startup
Industrial Biotech
Biomaterials
External Funding Raised
$1,900,000
Initiated
1 Nov 2022

At a Glance

Stage
TRL5: The core technology has moved beyond lab proof-of-concept and is now undergoing scale-up and formulation with partners, validating performance under near-commercial conditions.
Area
Biomaterials
Status
Ongoing
Patent Status
Patent filed

Project links

Lates Project Updates

24 March 2025
Read Update
10 February 2025
Read Update
3 Jan 2025
Read Update

Background

Forever chemicals (PFAS) shrug off heat, water and solvents, yet those same carbon-fluorine bonds let them linger for centuries. The CDC has detected PFAS in 97% of Americans’ blood. A 2025 EU study warns that decontaminating polluted sites could cost about €100 billion every year for decades, and 37 % of European surface waters already exceed safe PFAS limits. BioHalo’s microbial biohalogenation platform replaces toxic perfluoro groups with single-fluorine sites, yielding biodegradable BioFPolymers and tailor-made fluoromonomers while slashing fluorine use and by-products.


Startup Progress to Date

To date BioHalo has secured more than 12 million DKK (~€1.6 M) in total funding, including 8 M DKK from BioInnovation Insitute and 4 M DKK in matched grants. They're now in the process of validating and commercializing their new-to-market products F-PHB and NyFon materialsl for high-performance industrial applications.

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